The clinical history of an 8-year old, Domestic Shorthair, spayed female cat, affected by feline restrictive orbital myofibroblastic sarcoma (FROMS) is reexamined, from the first ophthalmological assessment, with exophthalmos, absent palpebral motility and exposure keratitis of the right eye, to the contralateral and oral extension of the tumour and death induced, 10 months later, by euthanasia. Results of the investigations (blood-chemistry tests, imaging, neurological examination, dental examination) and follow-up are presented, together with a review of the literature, in order to provide details about the pathogenesis of this unusual feline neoplasm with the purpose of improving the diagnosis and prognosis of affected patients in the future.