Disseminated intracranial meningioma in a cat: clinical, imaging and pathological findings

A 10-year-old Persian male cat was referred with a history of left head tilt, generalized ataxia and apathy developed 20 days before. The neurological examination showed obtundation and bilaterally reduced menace reaction. The suspected neuro-anatomical localization was consistent with a multifocal/ diffuse intracranial lesion. Tomographic examinations (CT, MRI) showed numerous (at least 11) intracranial masses, of variable size and similar tomodensitometric characteristics/signal intensity, compatible with neoplastic lesions. At the end of the imaging examinations the owner decided for euthanasia. At macroscopic examination, multiple nodular masses were evident, adherent to the dura mater. Histologically, the masses had a similar and overlapping appearance and were composed by spindle cells organized in undulated and swirling bundles with hyaline mineralized concentric bodies (psammoma bodies), infiltrating the brain parenchyma. The histological diagnosis
was compatible with multiple psammomatous meningioma.

Additional Info

  • Authors: 1 Binanti D., 2 Manfredi M., 2 Zani D.
  • Authors note: 1 Laboratorio di Analisi Veterinarie Sarzana (SP) | 2 Ospedale Veterinario Universitario, Centro Clinico Veterinario e Zootecnico Sperimentale di Lodi, Università degli Studi di Milano
  • Year: 2018
  • Reference: Veterinaria Year 32, n. 6, December 2018
  • Pages: 363 - 368
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