A 4-year-old neutered female Bull Terrier was presented with a 20-day history of unilateral nasal discharge and reverse sneezing. The dog did not respond to antibiotics. Histological examination revealed severe rhinitis with septate hyphae and smooth, oval, pigmented, unicellular conidia. Mycological cultures yielded pure colonies of filamentous fungi, macroscopically and microscopically identified as Scedosporium apiospermum. Identification was confirmed by MALDI-TOF analysis. Susceptibility tests were performed. The isolate resulted susceptible in vitro to Econazole and Miconazole, intermediate to Enilconazole and Clotrimazole and resistant to Amphotericin B, Fluconazole, Ketoconazole and Itraconazole. In the dog, S. apiospermum has been previously reported as the causative agent of nasal disease in two cases in Spain, one in New Zealand and one in Australia. To our knowledge, this is the first case of rhinitis caused by S. apiospermum reported in a dog in Italy.