External auditory canal atresia (EACA) is an anomaly involving the closure or absence of the ear canal and represents an occurrence reported in humans, dogs and cats but it has never been previously described in the ferret. The present clinical case describes the experience gained with a ferret affected by EACA referred to the clinic for a physical examination and diagnostic investigation in order to evaluate the degree of the anomaly. A computed tomography (CT) performed in sedation and without contrast agent showed the complete absence of the external ear canal, confirming the malformation.