Pseudo-placentational Endometrial Hyperplasia (PEH) in a bitch: clinical and hystopathological findings

A healthy female Labrador Retriever was referred to the University’s Reproduction Unit for a gynaecological examination and for monitoring of the oestrous cycle in anticipation of breeding. The bitch underwent natural mating and pregnancy was diagnosed on day 35 after breeding. The ultrasound examination revealed a mono gestational pregnancy and the presence of a parenchymatous structure with very scarce fluid content, consistent with the remnant of an empty gestational sac. At the end of pregnancy a caesarean section was performed. The puppy was alive and apparently healthy. After ovariohysterectomy various nodular structures were detected on the endometrium of both uterine horns. The histopathological diagnosis was of Pseudoplacentational Endometrial Hyperplasia (PEH), an uncommon pathological finding often misdiagnosed as Cystic Endometrial Hyperplasia (CEH).

Additional Info

  • Authors: Cartolano C., Cunto M., Zambelli D., Bini C., Küster D. G., Sarli G.
  • Authors note: Dipartimento di Scienze Mediche Veterinarie, Università degli studi di Bologna, Ozzano dell’Emilia
  • Year: 2016
  • Reference: Veterinaria Year 30, n. 4, August 2016
  • Pages: 1 - 5
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